Risk Assessment for Vial Sealing Machine

The Vial Sealing machine shall be an automatic machine, with preferably 8-12 heads. The machine shall be used to seal the duly stoppered vial filled with product in either lyophilized or in liquid form. The machine shall be suitable to handle different sizes of product filled vials as per requirement.

Sealing machine shall be used for crimping/sealing of the vials. Stoppered vials from the automatic unloading system of lyophilizer or from Vial Filling & Stoppering machine shall be conveyed to the infeed turntable of the sealing machine. Thereafter, conveyor belt shall feed the vials in to the star wheel & star wheel shall feed the stoppered vials to the sealing turret.

The sealing turret shall consist of 8-12 sealing heads which shall be identical. During transfer, the vials shall collect a seal from the end of the seal feed chute and imparts it in a proper orientation for the sealing. Sealing head shall skirt, spin & seals the seal on to the neck of the vials.

The complete Vial sealing machine along with the transfer system at the upstream of equipment shall be installed under oRABs system with Grade A classification.

The machine shall consist mainly of the following main components:

• Infeed turntable
• Vial Infeed belt
• Screw Feeder
• Vial infeed star wheel
• Sealing rotor/ turret
• Discharge star wheel
• Discharge conveyor
• Out feed turntable