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Analytical Method Validation Report for SLS (Cleaning Validation)

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ANALYTICAL METHOD VALIDATION REPORT FOR SODIUM LAURYL SULPHATE (SLS)

June 2, 2026 June 3, 2026

Cleaning Validation Protocol for SLS

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ANALYTICAL METHOD VALIDATION PROTOCOL FOR SODIUM LAURYL SULPHATE (SLS)

June 1, 2026 June 2, 2026

Diclofenac Sodium Assay – Acidification–Extraction Method The acidification–extraction assay method for Diclofenac Sodium is a widely used analytical procedure in pharmaceutical quality control laboratories. This method is based on converting Diclofenac Sodium into its free acid form through acidification, followed by extraction into an organic solvent and quantitative determination. It is especially useful for evaluating the purity and potency of raw materials and finished pharmaceutical formulations. Diclofenac Sodium is the sodium salt of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, inflammation, and swelling. Since the compound is soluble in water in its sodium salt form, acidification with a mineral acid such as hydrochloric acid converts it into diclofenac acid, which is less water-soluble and more soluble in organic solvents like chloroform or ethyl acetate. In this assay, a measured quantity of Diclofenac Sodium sample is dissolved in distilled water. The solution is then acidified carefully using dilute hydrochloric acid until the pH reaches an acidic range, usually around pH 2. Upon acidification, diclofenac precipitates or becomes extractable into an organic phase. The mixture is transferred into a separating funnel, and extraction is performed multiple times using a suitable organic solvent to ensure complete recovery of the drug. The combined organic extracts are filtered and evaporated to dryness or analyzed directly depending on the analytical protocol. Quantitative determination may be carried out gravimetrically, spectrophotometrically, or by titration. The assay result is calculated based on the amount of diclofenac recovered compared to the labeled or theoretical amount. This method provides reliable accuracy and reproducibility when performed under controlled laboratory conditions. Proper pH adjustment, efficient extraction, and complete solvent removal are critical factors influencing the assay outcome. The acidification–extraction technique remains an effective and economical method for routine pharmaceutical analysis of Diclofenac Sodium.

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DICLOFENAC SODIUM ASSAY (METHOD 4)

May 29, 2026 May 29, 2026

Diclofenac Sodium Assay - Acidification-Extraction Method 3

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DICLOFENAC SODIUM ASSAY – ACIDIFICATION – EXTRACTION METHOD 3

May 29, 2026 June 1, 2026

Great Scientist who served pharma

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GREAT SCIENTIST WHO SERVED PHARMA SECTOR

May 28, 2026 May 28, 2026

Gram Staining

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GRAM STAINING

May 26, 2026 May 28, 2026

Diclofenac Sodium Titration (Method 2)

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DICLOFENAC SODIUM ASSAY (TITRATION METHOD 2)

May 24, 2026 May 26, 2026

Diclofenac Sodium Assay (Titration)

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DICLOFENAC SODIUM ASSAY (TITRATION METHOD 1)

May 23, 2026 May 23, 2026

Paracetamol Assay (CD Method)

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PARACETAMOL ASSAY (CD METHOD)

May 23, 2026 May 23, 2026

Paracetamol Assay by UV Spectrophotometer

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PARACETAMOL ASSAY BY UV SPECTROPHOTOMETER

May 23, 2026 May 23, 2026

Chlorpheniramine Maleate

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CHLORPHENIRAMINE MALEATE ASSAY BY UV METHOD

May 23, 2026 May 23, 2026

CD method of Pseudoephedrine Hcl

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PSEUDOEPHEDRINE HCL (UV METHOD)

May 22, 2026 May 23, 2026

Manufacturing Process of Fungal Diastase & Pepsin Syrup

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MANUFACTURING PROCESS OF FUNGAL DIASTASE (50 MG) & PEPSIN (10 MG) SYRUP

May 22, 2026 May 22, 2026

Manufacturing Process of Aspirin Tablets USP 81 mg

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MANUFACTURING PROCESS OF ASPIRIN TABLETS USP 81 mg

May 21, 2026 May 21, 2026

Manufacturing Process of Aceclofenac Tablets 100 mg

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MANUFACTURING PROCESS OF ACECLOFENAC TABLETS 100 mg

May 20, 2026 May 20, 2026

Acarbose Tablets 25 mg

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MANUFACTURING PROCESS OF ACARBOSE TABLETS 25 mg

May 17, 2026 May 18, 2026

Manufacturing Process of Acetylcysteine Effervescent Tablets USP 600 mg

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MANUFACTURING PROCESS OF ACETYLCYSTEINE EFFERVESCENT TABLETS USP 600 mg

May 16, 2026 May 16, 2026

Purified Water System Components

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DECODING PURIFIED WATER SYSTEM COMPONENTS (CHAPTER 5)

May 14, 2026 May 14, 2026

Performance Qualificarton Test Analysis

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DECODING TYPICAL TESTS DURING PURIFIED WATER PERFORMANCE QUALIFICATION (CHAPTER 4)

May 13, 2026 May 14, 2026

Performance Qualification of Purified Water System

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DECODING PURIFIED WATER PERFORMANCE QUALIFICATION (CHAPTER 3)

May 12, 2026 May 13, 2026

Operational Qualification of Purified Water System

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DECODING PURIFIED WATER OPERATIONAL QUALIFICATION (CHAPTER 2)

May 7, 2026 May 9, 2026

Purified Water System Installation Qualification

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DECODING PURIFIED WATER INSTALLATION QUALIFICATION (CHAPTER 1)

May 6, 2026 May 6, 2026

Compressed Air Qualification in Pharma

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DECODING COMPRESSED AIR QUALIFICATION IN PHARMA

April 30, 2026 May 2, 2026

AHU QUALIFICATION

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DECODING AHU QUALIFICATION

April 23, 2026 May 2, 2026

Precipitations observed in Hydralazine Hydrochloride Injection

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Precipitations observed in Hydralazine Hydrochloride Injection

April 20, 2026 May 2, 2026

SOP for Effluent Treatment Plant in Pharma

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SOP for Effluent Treatment Plant in Pharma

April 11, 2026 May 2, 2026

SOP for De-Cartoning of Vials, Ampoules & Ophthalmics in Pharma

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SOP for De-Cartoning of Vials, Ampoules & Ophthalmics in Pharma

April 9, 2026 May 2, 2026

SOP for Filter Cleaning in Pharma

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SOP for Filter Cleaning in Pharma

April 8, 2026 May 2, 2026

SOP for Passivation in Pharma

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SOP for Passivation in Pharma

April 7, 2026 May 2, 2026

SOP for Cleaning of General Area Factory Footwear in Pharma

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SOP for Cleaning of General Area Factory Footwear in Pharma

April 6, 2026 May 2, 2026

SOP on First Aid in Pharma

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SOP on First Aid in Pharma

April 6, 2026 May 2, 2026

SOP for Cleaning & Sanitation of Premises in Pharma

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SOP for Cleaning & Sanitation of Premises in Pharma

April 4, 2026 May 2, 2026

SOP for Pest & Rodent Controls in Pharma

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SOP for Pest and Rodent Control in Pharma

April 4, 2026 May 2, 2026

SOP FOR HEALTH CHECKUP IN PHARMA

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SOP for Health Checkup in Pharma

April 3, 2026 May 2, 2026

SOP on Induction Program in Pharma

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SOP on Induction Program in Pharma

April 2, 2026 May 2, 2026

SOP for Cleaning of Drained of Out area premises (HR Department)

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SOP for Cleaning of Drained of Out area premises

April 2, 2026 May 2, 2026

Pellets in Pharma

Documents

PELLETS IN PHARMA

March 21, 2026 March 29, 2026

Aseptic Practices in Pharma

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ASEPTIC PRACTICES IN PHARMA

March 19, 2026 May 2, 2026

Packing SOP

Standard Operating Procedure

PACKING SOP IN PHARMA

March 6, 2026 May 2, 2026

Decoding Ampoules in Pharma

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DECODING AMPOULES IN PHARMA

February 23, 2026 May 2, 2026

USING BENZYL ALCOHOL AS PRESERVATIVES IN INJECTABLE VIALS

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USING BENZYL ALCOHOL AS PRESERVATIVES IN INJECTABLE VIALS (PICTORIAL)

December 13, 2025 December 13, 2025

Entry in Aseptic Area

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ENTRY INTO ASEPTIC AREA [PICTORIAL]

November 30, 2025 December 7, 2025

Operational Qualification of Vibro Sifter

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OPERATIONAL QUALIFICATION FOR VIBRO SIFTER [PICTORIAL]

November 30, 2025 December 7, 2025

Installation Qualification of Vibro Sifter

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INSTALLATION QUALIFICATION FOR VIBRO SIFTER [PICTORIAL]

November 29, 2025 December 7, 2025

Disinfectant Validation in Pharma

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DISINFECTANT EFFICACY VALIDATION [PICTORIAL]

November 23, 2025 December 7, 2025

Fogging in Pharma

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FOGGING IN PHARMA [PICTORIAL]

November 22, 2025 December 7, 2025

Daily Balance Verification

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DAILY BALANCE VERIFICATION [PICTORIAL]

November 16, 2025 December 7, 2025

Decartoning of Ampoules

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DECARTONING OF AMPOULES [PICTORIAL]

November 14, 2025 December 7, 2025

Personal Monitoring

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PERSONAL QUALIFICATION IN PHARMA [PICTORIAL]

November 8, 2025 December 7, 2025

Operation of Compression Machine

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OPERATION OF COMPRESSION MACHINE IN PHARMA [PICTORIAL]

November 3, 2025 December 7, 2025

Solvent Dispensing Area

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DECODING SOLVENT DISPENSING AREA IN PHARMA (PICTORIAL)

October 31, 2025 December 7, 2025

ENTRY PROCEDURE IN MANUFACTURING CORRIDOR

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ENTRY PROCEDURE IN MANUFACTURING CORRIDOR [PICTORIAL]

October 30, 2025 December 7, 2025

Operation of Vibro Sifter

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OPERATION OF VIBRO SIFTER (PICTORIAL)

October 27, 2025 December 7, 2025

RM Dispensing in Pharma

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RM DISPENSING IN PHARMA (PICTORIAL)

October 26, 2025 December 7, 2025

DECODING DIETHYL ALCOHOL (DEG) & ETHYL ALCOHOL (EG) NOTIFICATION (FOR ORAL LIQUIDS)

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DECODING DIETHYL ALCOHOL (DEG) & ETHYL ALCOHOL (EG) NOTIFICATION (FOR ORAL LIQUIDS) (PICTORIAL)

October 24, 2025 December 7, 2025

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DECODING BULGING PROBLEM IN TABLET STRIPS (PICTORIAL)

October 23, 2025 December 7, 2025

Staging Area

Documents

DECODING WAREHOUSE (CHAPTER 4 – STAGING AREA)

October 23, 2025 December 7, 2025

Quarantine Area

Documents

DECODING WAREHOUSE (CHAPTER 3 – QUARANTINE AREA)

October 22, 2025 December 4, 2025

Pharma plant and Premises

Documents

DECODING PHARMA PLANT & PREMISES (AS PER SCHEDULE M)

October 22, 2025 December 4, 2025

Risk Assessment for De-dusting Tunnel

Documents

DECODING WAREHOUSE (CHAPTER 2: RISK ASSESSMENT OF DE-DUSTING TUNNEL)

October 21, 2025 December 4, 2025

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