OINTMENTS QUALIFICATIONS IN PHARMA

Ointments qualifications in pharma plays a significant role. Ointments are cosmetic products that are applied externally to the skin. When applied to the skin, they frequently have an oily or greasy consistency and may feel “stiff.” Ointment bases come in three main categories: oleaginous (greasy) bases, which reject water; water-absorbing bases, which are also greasy but enable water to absorb; and water-miscible bases (vanishing creams or water-soluble bases).

Types of Ointments (On the basis of penetration):

1. Epidermic Ointment: These Ointments are intended to produce their action on the surface of the skin and produce local effect, they are not absorbed.
2. Endodermic Ointment: These Ointments are intended to release the medicaments that penetrate into skin.
3. Diadermic Ointment: These Ointments are intended to release the medicament that pass through the skin and produce systemic effect.

Ointments are made in the pharmaceutical industry by melting oil and aqueous phases in two distinct jacketed vessels with agitators to ensure correct mixing. Through valves and pipes, the two stages are transported to the main ointment vessel. Agitation is produced by the additional stirrers in the primary vessel. A consistent combination of the base and medication is essential during the entire procedure. Potential difficulties resulting from ineffective mixing and poor mixer design include the formation of agglomerates and non-uniform medication distribution in the base. In the dead places of the vessel, the content is not evenly mixed. As a result, additional actions are needed for recirculation to prevent product waste accumulated at dead spots.

1. INSTALLATION QUALIFICATION OF WATER PHASE VESSEL- 1260 LTRS
2. OPERATIONAL QUALIFICATION OF WATER PHASE VESSEL
3. INSTALLATION QUALIFICATION OF WAX PHASE VESSEL- 1260 LTRS
4. OPERATIONAL QUALIFICATION OF WAX PHASE VESSEL
5. INSTALLATION QUALIFICATION OF MANUFACTURING VESSEL-1765 LTRS.
6. OPERATIONAL QUALIFICATION OF MAIN MANUFACTURING VESSEL
7. INSTALLATION QUALIFICATION OF STORAGE TANK-1900 LTRS.
8. OPERATIONAL QUALIFICATION OF STORAGE TANK
9. INSTALLATION QUALIFICATION OF HOLDING VESSEL- 50 LTRS
10. OPERATIONAL QUALIFICATION OF HOLDING VESSEL 50 LTRS.
11. PERFORMANCE QUALIFICATION OF VESSELS
12. DESIGN QUALIFICATION OF TUBE FILLING MACHINE
13. INSTALLATION QUALIFICATION OF DOUBLE HEAD TUBE FILLING MACHINE
14. OPERATIONAL QUALIFICATION OF DOUBLE HEAD TUBE FILLING MACHINE
15. PERFORMANCE QUALIFICATION OF DOUBLE HEAD TUBE FILLING MACHINE
16. INSTALLATION QUALIFICATION OF CARTONING MC
17. OPERATIONAL QUALIFICATION OF CARTONING MC (CP-150)
18. PERFORMANCE QUALIFICATION OF CARTONING MACHINE
19. DESIGN QUALIFICATION FOR AIRJET BOTTLE CLEANING MACHINE
20. INSTALLATION QUALIFICATION FOR AIRJET BOTTLE CLEANING MACHINE
21. DESIGN QUALIFICATION FOR AUTOCARTONATOR
22. INSTALLATION QUALIFICATION FOR AUTOCARTONATOR
23. OPERATIONAL QUALIFICATION FOR AUTOCARTONATOR
24. PERFORMANCE QUALIFICATION PROTOCOL FOR AUTOCARTONATOR
25. PERFORMANCE QUALIFICATION REPORT FOR AUTOCARTONATOR
26. DESIGN QUALIFICATION FOR AUTOMATIC STICKER LABELLING MACHINE
27. INSTALLATION QUALIFICATION FOR AUTOMATIC STICKER LABELING MACHINE
28. OPERATIONAL QUALIFICATION FOR AUTOMATIC STICKER LABELING MACHINE
29. PERFORMANCE QUALIFICATION PROTOCOL FOR AUTOMATIC STICKER LABELING MACHINE
30. PERFORMANCE QUALIFICATION REPORT FOR AUTOMATIC STICKER LABELING MACHINE
31. DESIGN QUALIFICATION FOR CHECK WEIGHER MACHINE
32. INSTALLATION QUALIFICATION FOR CHECKWEIGHER MACHINE
33. OPERATIONAL QUALIFICATION FOR CHECK WEIGHER MACHINE
34. PERFORMANCE QUALIFICATION PROTOCOL FOR CHECK WEIGHER MACHINE
35. PERFORMANCE QUALIFICATION REPORT FOR CHECK WEIGHER MACHINE
36. DESIGN QUALIFICATION FOR CIP SYSTEM
37. INSTALLATION QUALIFICATION FOR CIP SYSTEM
38. OPERATIONAL QUALIFICATION FOR CIP SYSTEM
39. DESIGN QUALIFICATION FOR DEDUSTING TUNNEL
40. OPERATIONAL QUALIFICATION FOR DEDUSTING TUNNEL
41. DESIGN QUALIFICATION FOR DOUBLE HEAD AUTOMATIC FILLING, CLOSING AND SEALING MACHINE
42. DESIGN QUALIFICATION FOR DOUBLE HEAD TUBE FILLING MACHINE GAN COMBI
43. DESIGN QUALIFICATION FOR DYNAMIC PASS BOX
44. DESIGN QUALIFICATION FOR LEAK TEST APPARATUS
45. INSTALLATION QUALIFICATION FOR LEAK TEST APPARATUS
46. OPERATIONAL QUALIFICATION FOR LEAK TEST APPARATUS
47. DESIGN QUALIFICATION FOR MULTI MIX MANUFACTURING PLANT
48. INSTALLATION QUALIFICATION FOR MULTI MIX MANUFACTURING PLANT
49. OPERATIONAL QUALIFICATION FOR MULTI MIX MANUFACTURING PLANT
50. DESIGN QUALIFICATION FOR MULTI MIXER 250 kg
51. INSTALLATION QUALIFICATION FOR MULTI-MIXER 250 kg
52. OPERATIONAL QUALIFICATION FOR MULTI MIXER 250-kg
53. DESIGN QUALIFICATION FOR MULTI MIXER 500 kg
54. INSTALLATION QUALIFICATION FOR MULTI MIXER 500 kg
55. OPERATIONAL QUALIFICATION FOR MULTI MIXER 500-kg
56. PERFORMANCE QUALIFICATION PROTOCOL FOR MULTI MIXER 500-kg
57. DESIGN QUALIFICATION FOR RLAF
58. DESIGN QUALIFICATION FOR SEMI AUTOMATIC CRIMPING MACHINE
59. DESIGN QUALIFICATION FOR SINGLE HEAD SEMI AUTOMATIC TUBE FILLING, CRIMPING AND SEALING MACHINE
60. DESIGN QUALIFICATION FOR STIRRER
61. DESIGN QUALIFICATION FOR SIX HEAD LOTION FILLING MACHINE
62. DESIGN QUALIFICATION FOR STATIC PASS-BOX
63. DESIGN QUALIFICATION FOR VERTICAL LAMINAR AIR FLOW
64. INSTALLATION QUALIFICATION FOR AUTOMATIC TWO HEAD CAPPING MACHINE
65. INSTALLATION QUALIFICATION FOR DOUBLE HEAD TUBE FILLING MACHINE GAN COMBI
66. INSTALLATION QUALIFICATION FOR JACKETED MANUFACTURING TANK
67. INSTALLATION QUALIFICATION FOR MANUFACTURING TANK
68. INSTALLATION QUALIFICATION FOR SEMI-AUTOMATIC CRIMPING MACHINE
69. INSTALLATION QUALIFICATION FOR SINGLE HEAD SEMI AUTOMATIC TUBE FILLING, CRIMPING AND SEALING MACHINE
70. INSTALLATION QUALIFICATION FOR SIX HEAD LOTION FILLING MACHINE
71. INSTALLATION QUALIFICATION FOR SINGLE HEAD AUTOMATIC POWDER FILLING MACHINE
72. DESIGN QUALIFICATION FOR SINGLE HEAD AUTOMATIC POWDER FILLING MACHINE
73. OPERATIONAL QUALIFICATION FOR AUTOMATIC TWO HEAD CAPPING MACHINE
74. OPERATIONAL QUALIFICATION FOR DOUBLE HEAD FULLY AUTOMATIC FILLLING, CLOSING AND SEALING MACHINE
75. OPERATIONAL QUALIFICATION FOR DOUBLE HEAD TUBE FILLING MACHINE GAN COMBI
76. OPERATIONAL QUALIFICATION FOR MANUFACTURING TANK
77. OPERATIONAL QUALIFICATION FOR REVERSE LAMINAR AIR FLOW
78. OPERATIONAL QUALIFICATION FOR SEMI-AUTOMATIC CRIMPING MACHINE
79. OPERATIONAL QUALIFICATION FOR SINGLE HEAD AUTOMATIC POWDER FILLING MACHINE
80. OPERATIONAL QUALIFICATION FOR SINGLE HEAD SEMI AUTOMATIC TUBE FILLING, CRIMPING AND SEALING MACHINE
81. OPERATIONAL QUALIFICATION FOR SIX HEAD LOTION FILLING MACHINE
82. PERFORMANCE QUALIFICATION PROTOCOL FOR INDUCTION SEALING MACHINE
83. PERFORMANCE QUALIFICATION PROTOCOL FOR AUTOMATIC TWO HEAD CAPPING MACHINE
84. PERFORMANCE QUALIFICATION PROTOCOL FOR DOUBLE HEAD FULLY AUTOMATIC FILLING , CLOSING AND SEALING MACHINE
85. PERFORMANCE QUALIFICATION PROTOCOL FOR DOUBLE HEAD TUBE FILLING MACHINE GAN COMBI
86. PERFORMANCE QUALIFICATION PROTOCOL FOR MANUFACTURING TANK
87. PERFORMANCE QUALIFICATION PROTOCOL FOR HOT AIR OVEN
88. PERFORMANCE QUALIFICATION PROTOCOL FOR MULTI-MIX MANUFACTURING PLANT
89. PERFORMANCE QUALIFICATION PROTOCOL FOR SEMI-AUTOMATIC CRIMPING MACHINE
90. PERFORMANCE QUALIFICATION PROTOCOL FOR SHRINK WRAPPING MACHINE
91. PERFORMANCE QUALIFICATION PROTOCOL FOR SINGLE HEAD AUTOMATIC POWDER FILLING MACHINE
92. PERFORMANCE QUALIFICATION PROTOCOL FOR SINGLE HEAD SEMI AUTOMATIC TUBE FILLING, CRIMPING AND SEALING MACHINE
93. PERFORMANCE QUALIFICATION PROTOCOL FOR SIX HEAD LOTION FILLING MACHINE
94. PERFORMANCE QUALIFICATION REPORT FOR DOUBLE HEAD FULLY AUTOMATIC FILLING , CLOSING AND SEALING MACHINE
95. PERFORMANCE QUALIFICATION REPORT FOR DOUBLE HEAD TUBE FILLING MACHINE GAN COMBI
96. PERFORMANCE QUALIFICATION REPORT FOR HOT AIR OVEN
97. PERFORMANCE QUALIFICATION REPORT FOR JACKETED MANUFACTURING
98. PERFORMANCE QUALIFICATION REPORT FOR MANUFACTURING TANK
99. PERFORMANCE QUALIFICATION REPORT FOR MULTI-MIX MANUFACTURING TANK
100. PERFORMANCE QUALIFICATION REPORT FOR SEMI- AUTOMATIC CRIMPING MACHINE
101. PERFORMANCE QUALIFICATION REPORT FOR SHRINK WRAPPING MACHINE
102. PERFORMANCE QUALIFICATION REPORT FOR SINGLE HEAD AUTOMETIC POWDER FILLING MACHINE
103. PERFORMANCE QUALIFICATION REPORT FOR SIX HEAD LOTION FILLING MACHINE
104. PERFORMANCE QUALIFICATION REPORT FOR SIX HEAD LOTION FILLING MACHINE