Line clearance in the pharmaceutical industry is a critical process that ensures a production line is free from contaminants, previous product residues, and unauthorized materials before starting a new batch or product. It helps maintain Good Manufacturing Practices (GMP) and prevents cross-contamination.
A typical Line Clearance Checklist involves:
1. Removing previous product residues – Cleaning machines, tools, and work areas.
2. Checking materials & labels – Ensuring only approved materials are present.
3. Inspecting equipment setup – Verifying calibration and operational readiness.
4. Confirming personnel readiness – Proper gowning and hygiene compliance.
5. Approving documentation – Line clearance checklists and records.
